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Graft Survival Following Organ Transplant

The probability of a graft surviving at various time points following organ transplantation. Graft failure, re-transplantation and patient death are all considered graft failures.

Higher probabilities are desirable.

Data updated:
Data availability: to (calendar years)
Geographic coverage
All provinces/territories except Quebec
Reporting level
National, Province/Territory
Calculation

Cumulative probability of a transplanted organ (first kidney, liver, lung or heart) continuing to function at 90 days, 1 year, 3 years and 5 years after transplantation based on Kaplan-Meier survival analysis. Survival analysis considers time at risk for graft failure to be the time between transplantation and graft failure, death or censoring at either loss to follow-up or the end of the study period.

Unit of analysis: Transplanted organ

Note that bilateral kidney or lung transplants are counted only once toward this indicator. 

The following are included:

  1. Age 18 or older 
  2. Transplantation of a kidney, liver, heart or lung

Definition of organ transplantation

  1. Kidney: Canadian Organ Replacement Register (CORR) organ type code beginning with 1
  2. Liver: CORR organ type code beginning with 2
  3. Heart: CORR organ type code 30
  4. Lung: CORR organ type code beginning with 4

The following are excluded:

  1. Out-of-country transplants (CORR facility code 88888) 
  2. Organ retransplantation (graft number is greater than 1)
  3. Transplantation of several organ types in 1 surgery (records for multiple organ types for 1 surgery, or organ type code 43 or 90)
  4. For liver or lung recipients, transplantations from a living donor (donor type code is not 01)

Censor date

The censor date is the last day of follow-up. If a patient’s post-transplant care is reported to be transferred from the facility of their transplant surgery, that date of transfer is considered the censor date.

Failure date

The date of the first of the following events as reported in CORR is considered the failure date:

  1. Patient death
  2. Graft failure
Denominator

Not applicable

Numerator

Not applicable

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Source

Canadian Organ Replacement Register, Canadian Institute for Health Information.

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Notes

Certain metric values were suppressed or modified for confidentiality reasons in accordance with CIHI’s privacy policy. These values are identified with the text “Suppressed” in the data tables and hover-over tool tip.

The dash (—) indicates that no data is available. Select different parameters or reset the chart.

Source

Canadian Organ Replacement Register, Canadian Institute for Health Information.

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Name

Graft Survival Following Organ Transplant

Short/Other Names

Graft Survival

Description

The probability of a graft surviving at various time points following organ transplantation. Graft failure, re-transplantation and patient death are all considered graft failures.

Rationale

Organ transplantation restores organ function in the recipient, and the graft ideally lasts for the rest of the patient’s life. The time that a graft lasts until patient death or graft failure is thus a key indicator of the quality of the transplantation system.

Interpretation

Higher probabilities are desirable.

HSP Framework Dimension

Health system outcomes: Improve health status of Canadians

Targets/Benchmarks

Not applicable

Available Data Years

to (calendar years)

Geographic Coverage

  • All provinces/territories except Quebec

Reporting Level/Disaggregation

  • National
  • Province/Territory
  • Sex
  • Age 
  • Organ
  • Neighbourhood income quintile of patient residence

Indicator Results

Not applicable

Update Frequency

Every year

Latest Results Update Date

Updates

Not applicable

Description

Cumulative probability of a transplanted organ (first kidney, liver, lung or heart) continuing to function at 90 days, 1 year, 3 years and 5 years after transplantation based on Kaplan-Meier survival analysis. Survival analysis considers time at risk for graft failure to be the time between transplantation and graft failure, death or censoring at either loss to follow-up or the end of the study period.

Unit of analysis: Transplanted organ

Note that bilateral kidney or lung transplants are counted only once toward this indicator. 

The following are included:

  1. Age 18 or older 
  2. Transplantation of a kidney, liver, heart or lung

Definition of organ transplantation

  1. Kidney: Canadian Organ Replacement Register (CORR) organ type code beginning with 1
  2. Liver: CORR organ type code beginning with 2
  3. Heart: CORR organ type code 30
  4. Lung: CORR organ type code beginning with 4

The following are excluded:

  1. Out-of-country transplants (CORR facility code 88888) 
  2. Organ retransplantation (graft number is greater than 1)
  3. Transplantation of several organ types in 1 surgery (records for multiple organ types for 1 surgery, or organ type code 43 or 90)
  4. For liver or lung recipients, transplantations from a living donor (donor type code is not 01)

Censor date

The censor date is the last day of follow-up. If a patient’s post-transplant care is reported to be transferred from the facility of their transplant surgery, that date of transfer is considered the censor date.

Failure date

The date of the first of the following events as reported in CORR is considered the failure date:

  1. Patient death
  2. Graft failure

Type of Measurement

Percentage or proportion

Denominator

Description:

Not applicable

Inclusions:

Not applicable

Exclusions:

Not applicable

Numerator

Description:

Not applicable

Inclusions:

Not applicable

Exclusions:

Not applicable

Geographic Assignment

Place of service

Data Sources

  • CORR

Caveats and Limitations

Note that the methodology for this indicator varies slightly from the graft survival methodology in CORR reports. The main differences are the inclusion and exclusion criteria. Use caution when comparing results across products.

Trending Issues

Not applicable

Comments

Future reporting will use data from the new Canadian Organ Donation and Transplantation Data System (CanODT) once it is available.

References

Not applicable

How to cite:

Canadian Institute for Health Information. Graft Survival Following Organ Transplant. Accessed April 25, 2025.