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2012 HSMR Methodology

Introduction | Results

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Technical Notes for the 2012 HSMR Public Release

Definition

The hospital standardized mortality ratio (HSMR) is a ratio of the actual number of in-hospital deaths in a region or hospital to the number that would have been expected based on the types of patients a region or hospital treats.

  Observed Deaths  
HSMR = ______________ X 100
 
  Expected Deaths  

Method of calculation

Numerator: Observed deaths, or actual number of in-hospital deaths that occurred in a hospital or region.

Denominator: Expected deaths, or number of deaths that would have occurred in a hospital or region had the mortality of these patients been the same as the mortality of similar patients across the country, based on the reference year (2009–2010).

Regional or corporation-level HSMRs are calculated as the sum of observed deaths for all acute care sites divided by the sum of expected deaths for all acute care sites multiplied by 100. Regional and facility HSMR results are based on where patients were treated, not where they lived.

Inclusion criteria

  1. Discharge between April 1 of a given year and March 31 of the following year.
  2. Admission to an acute care institution.
  3. Discharge with diagnosis group of interest (that is, one of the diagnosis groups that account for approximately 80% of in-hospital deaths).
  4. Age at admission between 29 days and 120 years.
  5. Sex recorded as male or female.
  6. Length of stay up to 365 consecutive days.
  7. Admission category is elective or emergent/urgent.
  8. Canadian resident.

Exclusion criteria

  1. Cadavers.
  2. Stillborns.
  3. Sign-outs (that is, discharged against medical advice).
  4. Patients who did not return from a pass,
  5. Neonates (age of admission less than or equal to 28 days).
  6. Records with brain death as most responsible diagnosis code.
  7. Records with palliative care as most responsible diagnosis code.

Logistic regression models

Some types of patients are more likely than others to die in hospital. For example, older patients and those with certain health problems on admission (comorbidities) are at higher risk. Since these risk factors can change over time and vary from place to place, the HSMR calculation takes these differences into account using a statistical technique known as logistic regression.

For each of the HSMR diagnosis groups, the HSMR logistic regression models are fitted with age, sex, length-of-stay (LOS) group, admission category, comorbidity group and transfers as independent variables. The models are based on data from all acute hospitals in Canada. Coefficients derived from the logistic regression models are used to calculate the probability of in-hospital death. The expected number of deaths for a hospital, corporation or region is based on the sum of the probabilities of in-hospital death for eligible discharges from that organization. The 95% confidence interval is calculated using Byar’s approximation.

Interpretation

A ratio equal to 100 suggests that there is no difference between a local mortality rate and the average national experience, given the types of patients cared for. An HSMR greater or less than 100 suggests that a local mortality rate is higher or lower, respectively, than the national experience.

The confidence intervals describe the precision of the HSMR estimate. The upper and lower confidence intervals are estimated to contain the true value of the HSMR 19 times out of 20 (95% confidence interval). A confidence interval that includes 100 suggests that the HSMR is not statistically different from the 2009–2010 baseline of 100.  HSMR results whose confidence interval does not include 100 and are therefore statistically different from the 2009–2010 baseline are denoted with a symbol in the report.

While HSMR adjusts for a number of factors affecting the risk of in-hospital mortality, it does not control for everything. Therefore, HSMR results are most useful in tracking trends over time.

Data source

Discharge Abstract Database, Canadian Institute for Health Information.
Hospital Morbidity Database, Canadian Institute for Health Information.

Reference period

The reference year for HSMR calculations is 2009–2010. To allow for comparisons over time, the coefficients derived from the model using the reference year are used to determine expected deaths for all reported years.

Comprehensiveness

Results are only reported for regions and acute care facilities that meet a statistical threshold for public reporting: at least 2,500 qualifying discharges in each of the last three years being reported i.e. 2009–2010, 2010–2011 and 2011–2012

Bibliography

Alexandrescu, R. et al. “Logistic vs Hierarchical Modeling: An Analysis of a Statewide Inpatient Sample.” Journal of American College of Surgeons 213, 3 (2011): pp. 392–401.

Bottle, A., B. Jarman and P. Aylin. “Hospital Standardized Mortality Ratios: Sensitivity Analyses on the Impact of Coding.” Health Services Research 46, 6 Part 1 (2011): pp. 1741–1761.

Bottle, A., B. Jarman and P. Aylin. “Strengths and Weaknesses of Hospital Standardised Mortality Ratios.” BMJ 342 (2011): p. 7116.

Breslow, N. E. and N. E. Day. Statistical Methods in Cancer Research: Volume II—The Design and Analysis of Cohort Studies. Lyon, France: International Agency for Research on Cancer, 1987.

Jarman, B. et al. “Explaining Differences in English Hospital Death Rates Using Routinely Collected Data.”BMJ 318 (1999): pp. 1515–1520, accessed from <http://bmj.bmjjournals.com/cgi/content/full/318/7197/1515>.

Jarman, B., A. Bottle and P. Aylin. “Monitoring Changes in Hospital Standardised Mortality Ratios.” BMJ 330 (2005): p. 329.

Quan, H. et al. “Updating and Validating the Charlson Comorbidity Index and Score for Risk Adjustment in Hospital Discharge Abstracts Using Data From 6 Countries.” American Journal of Epidemiology 173, 6 (2011): pp. 676–682.

Diagnosis Groups That Account for 80% of Acute Care In-Hospital Mortality

Diagnosis Group

Description

A04

Other bacterial intestinal infections

A41

Sepsis

C15

Malignant neoplasm of oesophagus

C16

Malignant neoplasm of stomach

C18

Malignant neoplasm of colon

C22

Malignant neoplasm of liver and intrahepatic bile ducts

C25

Malignant neoplasm of pancreas

C34

Malignant neoplasm of bronchus and lung

C50

Malignant neoplasm of breast

C61

Malignant neoplasm of prostate

C67

Malignant neoplasm of bladder

C71

Malignant neoplasm of brain

C78

Secondary malignant neoplasm of respiratory and digestive organs

C79

Secondary malignant neoplasm of other sites

C80

Malignant neoplasm without specification of site

C83

Diffuse non-Hodgkin’s lymphoma

C85

Other and unspecified types of non-Hodgkin’s lymphoma

C90

Multiple myeloma and malignant plasma cell neoplasms

C92

Myeloid leukemia

E11

Diabetes mellitus type 2

E86

Volume depletion

E87

Other disorders of fluid, electrolyte and acid-base balance

F03

Unspecified dementia

F05

Delirium, not induced by alcohol and other psychoactive substances

G30

Alzheimer’s disease

G93

Other disorders of brain

I21

Acute myocardial infarction (AMI)

I24

Other acute ischemic heart diseases

I25

Chronic ischemic heart disease

I26

Pulmonary embolism

I35

Nonrheumatic aortic valve disorders

I46

Cardiac arrest

I48

Atrial fibrillation and flutter

I50

Heart failure

I60

Subarachnoid haemorrhage

I61

Intracerebral haemorrhage

I62

Other nontraumatic intracranial haemorrhage

I63

Cerebral infarction

I64

Stroke, not specified as haemorrhage or infarction

I70

Atherosclerosis

I71

Aortic aneurism and dissection

J18

Pneumonia

J44

Other chronic obstructive pulmonary disease

J69

Pneumonitis due to solids and liquids

J80

Adult respiratory distress syndrome

J84

Other interstitial pulmonary diseases

J90

Pleural effusion, not elsewhere classified

J96

Respiratory failure, not elsewhere classified

K26

Duodenal ulcer

K55

Vascular disorders of intestine

K56

Paralytic ileus and intestinal obstruction without hernia

K57

Diverticular disease of intestine

K63

Other diseases of intestine

K65

Peritonitis

K70

Alcoholic liver disease

K72

Hepatic failure

K74

Fibrosis and cirrhosis of liver

K85

Acute pancreatitis

K92

Other diseases of digestive system

L03

Cellulitis

N17

Acute renal failure

N18

Chronic renal failure

N39

Other disorders of urinary system

R53

Malaise and fatigue

R57

Shock, not elsewhere classified

R64

Cachexia

S06

Intracranial injury

S32

Fracture of lumbar spine and pelvis

S72

Fracture of femur

T81

Complications of procedures, not elsewhere classified

T82

Complications of cardiac and vascular prosthetic devices, implants and grafts

Z54

Convalescence

Contact us: hsmr@cihi.ca